Searchable abstracts of presentations at key conferences in endocrinology

ea0023p31 | (1) | BSPED2009

Prophylactic Thyroidectomy in Children with Multiple Endocrine Neoplasia Type 2

Morkane Clare , Raptis Dimitri , Brain Caroline , Spoudeas Helen , Dattani Mehul , Hindmarsch Peter , Piero Agostino , DeCoppi Paolo , Kurzawinski Tom

Background: The most common cause of death in patients with Multiple Endocrine Neoplasia type 2 is medullary thyroid carcinoma. All patients with MEN2 develop this cancer and Prophylactic Thyroidectomy (PT) is recommended to prevent malignant transformation.Method: This study reviews our experience of treating children identified as carriers of a RET mutation diagnostic of MEN-2A. Data was collected by reviewing patient notes and hospital electronic data...